Tirzepatide vs Semaglutide: Price Comparison
Nightly $/mg price comparison of Tirzepatide and Semaglutide across US research-peptide vendors. As of 2026-10-10, the lower listed price per mg is Tirzepatide ($1.097/mg) vs Semaglutide ($1.107/mg). At the median, Semaglutide is listed at $8.00/mg against $5.20/mg for Tirzepatide, a gap of $2.80/mg (1.5×). This is a price comparison only — not a comparison of potency, dosing, safety, or efficacy, and not medical advice.
| Metric | Tirzepatide | Semaglutide |
|---|---|---|
| Lowest listed $/mg | $1.097/mg | $1.107/mg |
| Median listed $/mg | $5.20/mg | $8.00/mg |
| Middle half of listings ($/mg) | $3.587/mg – $8.208/mg | $5.00/mg – $12.00/mg |
| Vendors tracked | 133 | 95 |
| 30-day price trend | +0.81% (30d) | +0.01% (30d) |
| Cheapest vendor | Peptaura | Peptaura |
| Stores listing both | 90 stores list both (Tirzepatide: 133, Semaglutide: 95) | |
Numbers for journalists
- Lowest listed price per mg: Tirzepatide $1.097/mg, Semaglutide $1.107/mg.
- Median listed price per mg: Tirzepatide $5.20/mg, Semaglutide $8.00/mg.
- At the median, Semaglutide is listed at 1.5 times the price per mg of Tirzepatide.
- Stores with a comparable listing: Tirzepatide 133, Semaglutide 95; 90 list both.
- Change in median price per mg over 30 days: Tirzepatide +0.81% (30d), Semaglutide +0.01% (30d).
Source: The Peptide Index (Peptide Price History), Tirzepatide vs Semaglutide: price comparison, nightly crawl of public vendor catalog pages, data as of 2026-10-10. Method: how $/mg works. You may quote these figures with a link to this page.
Tirzepatide vs Semaglutide price questions
Which is cheaper per mg, Tirzepatide or Semaglutide?
As of 10 Oct 2026, the median listed price is $5.20/mg for Tirzepatide and $8.00/mg for Semaglutide, so Tirzepatide has the lower median $/mg. By lowest single listing the lower figure is Tirzepatide at $1.097/mg against $1.107/mg for Semaglutide. Prices are single-vial, ex-shipping and refreshed nightly; this says nothing about quality or suitability.
How much more expensive is Semaglutide than Tirzepatide per mg?
As of 10 Oct 2026, the median listed price of Semaglutide is $2.80/mg higher than Tirzepatide ($8.00/mg against $5.20/mg), a ratio of 1.5 to 1. Medians are across each compound's current comparable single-vial listings.
How many stores list both Tirzepatide and Semaglutide?
As of 10 Oct 2026, 90 tracked stores list both. Tirzepatide is priced by 133 stores and Semaglutide by 95. Listing a store is a statement about price data, never an endorsement.
Have Tirzepatide and Semaglutide prices changed in the last 30 days?
The 30-day change in the daily median $/mg is +0.81% for Tirzepatide and +0.01% for Semaglutide. Days the crawl missed are left out, never filled in.
Does this page compare Tirzepatide and Semaglutide beyond price?
No. It compares listed prices in US dollars per milligram, vendor counts and the 30-day price trend only. It does not compare potency, dosing, safety or efficacy, and it is not medical advice. Sale prices and shipping are not included.
Research Use Only. Publicly listed vendor prices, ex-shipping, normalized to $/mg and refreshed nightly — the same methodology and data as each compound’s own page (see how $/mg works and how we verify). Not medical advice, not a recommendation to purchase, and not a claim about potency, dosing, safety, or efficacy of either compound.